After short-term injuries, the connective tissue defect is filled with what in 3-4 days?

• A. Granulation tissue
• B. Scar tissue
• C. Fibrosis tissue
• D. Necrotic tissue

Answer: (A)

During the early wound-healing phases, about 3–4 days after a short-term connective tissue injury, the defect is filled by granulation tissue. This tissue is rich in new blood vessels (angiogenesis), activated fibroblasts, inflammatory cells, and extracellular matrix. It fills the wound bed, providing a vascular, semi-soft scaffold that supports epithelialization and sets the stage for remodeling into mature tissue. Scar tissue forms later as this granulation tissue matures and collagen reorganizes; fibrosis refers to excessive collagen deposition and is not the initial fill in this time frame. Necrotic tissue would be dead tissue that should be cleared and would hinder healing rather than fill the defect.